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amiss (adj) wrong; not in perfect shape.
When you feel that something is amiss, you suspect that something is wrong. When things are not happening the way you want, something is amiss. If something goes amiss at some point, your plans may fail.
- When the profits were not up to the expectations of the chairman of the company, he felt that something was amiss in the marketing department, and called for a meeting to review the marketing strategies.
- The ground staff felt that something was certainly amiss when they lost radio contact with the plane on its maiden trip.