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deranged (adj) mad; insane.
A deranged person is mad. They are mentally ill and cannot think or act normally. A deranged attacker is a person who, because they are mad, attacks others. Deranged laugh is the laugh of a person who is insane, or who laughs as though they were insane.
- Depressed over his repeated failure, Harry became deranged and had to be admitted in a mental asylum.
- There appears to be no absolute therapy for restoring deranged people to normal mental health. Very rarely do we come across deranged persons being totally and permanently cured of their madness.