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heedless (adj) disregarding; not paying attention to.
A person is heedless of their safety if they do not care about their safety. A person heedless of others' warnings does not pay attention to them. They disregard the warnings.
- He continued to get drunk night after night heedless of his doctor's warnings that his addiction was ruining his kidney.
- Heedless of his own safety and that of the school children in the bus, the drunken driver drove on rashly and that led to the accident resulting in ten children's death.